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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954fcf517d2d100f31f11f648ef43a7c8f44e8f38f6c139db7831cfb76eb3e25' 
  AND token = '7UUtmjLSoSTDEmy3R1/e/oIkoxXceVKT2sFJU1Il0/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}