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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa45d564795bfdcca888b1e22b4fb0cd2cb4a82e864405baa79dbf3e440b31fd' 
  AND token = '36Aj+nu3vRZzy6N7FCN0rci/MqTKd4Uzuiw+zaQ7MDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}