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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76ac505fb94e454f4bac3dd39a9ac422b6cb8463e2c5f3a1f9c59d327d5325a7' 
  AND token = 'OHOkGaLg0feFu+KLDq40mH+m0sQchpJjB9DeZ1IEPQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}