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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf7a516313e1ace06d3315418becfd25787d668b8fdbacaa70dbf4a5b2dd456' 
  AND token = 'Sr1CN9ZtAB7XSxio/bfiGFj3j2FkXr8D6wU7rMb6U14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}