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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5f5f4b85d4b98ac4847fddfea65ad927ad36e0ccb10d58d7e0a52e1afc0c4d' 
  AND token = 'GSsIX3iW57ynNwT60cosspYZRELt/hfCmn851k1X63g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}