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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ff9c21d81c69e9aede76b3a579641796a663f9666f1d1bf34887de10eca9a6' 
  AND token = '0cK6cb2vIVzy0WV/ySYTCOKy3PGzXwGV4CeNEXSee/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}