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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c82c614ab330e73dc0ca4315194b42823a15b709128abb3cd78aeae6648c3f6' 
  AND token = 'T1TDUutdcy/URzisa3XVa57FRAMyRgF5kJHPkvNnM50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}