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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320c31a9d80895731f737f1d04ecb4b0d507e604620c50417f06fc366ac8fb0a' 
  AND token = 'U3PnndW2IVtbF2Yee1CWOPsRsVnfOTsvKpVrotYNVBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}