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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07d9ec07869d5b83e8fa1b8cfc8729ba570b90caacd6a7529cb354c3aab28e0' 
  AND token = '274EbOEr1L5Jx2DGxc7r2XNm3Hj74ZakJjfNIEJOhnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}