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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0de5dbc8d41d525db11a70e0de7107a1a4726dc5e5452d9ace525845a7960c' 
  AND token = 'Rsbxl8ArZmHIT971hPV6deJAOR1E/fWCRgCUPc8NCUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}