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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8e0f6e1f28f2c4215b88b072bcc6109f0a150f2b0ec1b13a651a3fbdce3f2b' 
  AND token = 'U/8bO/V71E655knPDNpYWU/aaF6Eiou9+xGn7Gl0aDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}