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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bae3d43d352969b072efa4d56c2967f445b50bb5f60d4c6233a28342f824a18' 
  AND token = 'VcoUSgVJAk0MYsu32P9l+TdUmF7c5Bj4sHtCU+WFmbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}