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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bf8d973960ab3a401edadc0336ea98ea027ce9459ec9a948c49fe315cbc7c54' 
  AND token = 'KfW3NfgVMOBBrJVU4hc/UCDRNekx+aV/iYhvX7U0nwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}