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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1cfb6408407c7adb292c64d0c51cfa91c0cede66bdef485570c26d7a8759b1f' 
  AND token = 'Rt3I9FxJ7bLRRymrZqqi9SB/b9shCIR1aPyG/KmdZyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}