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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822e360d7ee383316d517b980847fa10024825dcd386107a34665ccf5a98a409' 
  AND token = 'FCFmZyPF34nHTU0yr8O4H+SF1Bn67FlAp2TMYo+sfNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}