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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dd15a8f6a61d86ed02500b12dd6c3b718b13193b0cd5480254d52023e3b13d' 
  AND token = 'pkQi5FG+ldPJQ1zdBX/qtW3fTlh/HL80Lbs6W4LxZqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}