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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b382647a72d8ac1ee581f210f9d949bbe5cfe2560642e6e1294a445e5f7c1c7' 
  AND token = 'XE5F5943tQ8tFSAUlz6lDH05xi9jSqC0zUrnAvt0Y8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}