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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241e40cace921f4ccef4f304a10a49c730ea66334ae9052d27440272e30e6dd9' 
  AND token = 'eIM28xFgXZ+RvN2Z6yY5Uo7okUlvb+stk7UxynaforI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}