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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d4f499c8e04d9fb7a88a900ebbb6ee7920a5fbad3b2963aafde9a66473702f' 
  AND token = 'sHNS6m1TWHGxpc7On4QejxPy7LOJHrynRPuIq3hlYvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}