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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '304f9dd66f3aae0045a94e6286c243ac3f0a99bacddf590cd12c37d2036fcef0' 
  AND token = 'a4aM6Lx1a9V5rnNuWHCGwNYeN1v5CRfrr+1nP+Tce4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}