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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afe2462e1b270faa04af348e1aebb2564408dca760cbfff9a7de4bcd65d8b54' 
  AND token = '/8x8Taiom/7YczoiOQKQoS0nZMV8MnLN+NmKo6qetJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}