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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cfd6d1a18ab2c0b21090dcbcba1d9a315bdebd4aee414212c3577872b45873a' 
  AND token = '6nIGThX5eAKEhhl2acUkgPWpUSP7b1u96CVAubkyk6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}