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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c042054515ee9f4f9dc4b7eca2f8d8035e6af6ae97bab418d866967fc236eb1' 
  AND token = '37ZtaCAbtVMMeSgSMekx+Y3A8D70m7Ack06+XkUJknw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}