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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254c49f6b30ee642e2224ed342fed2de62dde82c565287acc001dac79c9b39d2' 
  AND token = 'dHz8Oz88odjoaUMhrdvyU4298w/VGWM5CkincEjhsM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}