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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac29d4a0eb860d2685f7518efca2db5160014533badd280d5fa9a320e87c4c5' 
  AND token = 'UZnspXtm+venVWVcZkzh93at1aP25PwLytjgHpPGW04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}