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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d15c190ee80f9b5670b54d20ce72502c45a89f43ac5a2021af43a12502b703' 
  AND token = 'jrhryP+hoSUTgesZTpBBBUQLS6R+ws9NftGjkCY97ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}