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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4df03bb475a3e9b08e144394dfda6e7124bb567644dc9bc8bd6f8a458b0a51' 
  AND token = 'WxMH5QO3xtLV8a+1dQgpFMoCalvKQJ5+1mTxw0wkILE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}