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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f215cc8675bbc65473726128e1a4cc1803d6f66ec240720797690d67b2a974dd' 
  AND token = 'IVerhkWnrjwdSlm+IG4tj09niINijOkkBS8ppZa9Xrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}