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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd2ba048eb8665d5ef5ec312006f53e0bf4cebc9506669cac37ca9efe103377' 
  AND token = 'AMZ+uGw4D8r4e0F3+0RCaUDjJMAog0L9xc/xBUBNhTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}