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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efdcd417c65437c51df2347cf33f39b18ef1c8f2db9d3e246045df05a18608ce' 
  AND token = 'JJBkd49EQdb+mh5kr0jIfxKfeSbpFfDD+xGC1MgJgB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}