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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b6167653a17ff2e54386a8a66ba16d706e5bc76d3bd312004e34dba4575ba2' 
  AND token = 'ESG88oh2vR5FTPpvoW/g1cohDNCE2N63PYM2iBY/YkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}