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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5145a63210bdacaca0a32abc81d00fc1d37407f09e8a5f162676b89fe94012e5' 
  AND token = 'balAEeDTXWC+AxWtRvztyQUvPvpoH0eo9s+XpmUDKJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}