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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a16a99b9ef86f523bf6e8078b612e0120c5f4dedfe4fde9c89799a73fc52f80' 
  AND token = 'IOFBepUPw1E4n6Y6ch0NfNXX9NFIxC+wGHSe2qAxf/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}