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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2487406b14a20427b9c0926dfa1f358b0aa0b11da362f957d62b45d29f7a662' 
  AND token = '27k3n5e7HPNkTwlxhsTB2xwULQkqCrM44KfgMCdcenk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}