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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2065a8af36f7333089b5a0c0634d782c44f45f4adc9d5aedc48e8cd5cdd0974' 
  AND token = 'xUD5tA2NPSOM/7ToEtzWPGLZ+36sE2/XlG9j2th/6Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}