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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c479366dad9b47e612a1699ccf1216e0d1fac4bd81078e104f71856770db146' 
  AND token = 'iV5IS8B659OsnugW+3ugMO4jKspsLx29WvTLIyb8zyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}