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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38accd5d8c6a9393cf1657c91be38f713296a98c8740d4a1d4a1c8b85cf349d' 
  AND token = '2zIQjWdWEG+Ui5CDPDGFL+0JYr+cj9ErTTz5YzlLt58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}