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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4526a1ea40fd7f8f519fdec0959b309a92c9813b7e2cc2fe377477676a10471d' 
  AND token = 'E8qTT+uk48rmMNzenU6PJe8MT3EPIuwH5Ao8bsgPXSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}