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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390c24623ac2dcfe471cc8faf5680c6684b274a1e4e58e9978749ab1419ca199' 
  AND token = 'DWQcUF85GvPj7ilkp8L1oM3rwdpntSeDHuXWm9GwU1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}