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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646a631abb3e885590c3d79a736a834a0ad710807f8e7bb7bac637959ac08b0f' 
  AND token = 'zfqtukRF5dG+ZxQyb1Ylw5fkAQi/w8RB7KgKv6E3jco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}