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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af79752e1ed16a6496e1484589186b7c8fd341c1b20617eb9d63335ae3afdc0f' 
  AND token = 'jX+cT+2iADbK+IJLSBdYY1IwYsRW7NEvYcBRcNl0anc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}