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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35750fbdce5fd46e031fe6706a8078eb75a3158b4cb6c4c502a37e9d2334f7d' 
  AND token = 'OylrPqF0NGEO1tBe2K7LBBU7BK2MqqACpVd18ICIFQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}