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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ed75bf591172ba94510a6063be8b1280f7f7c2f005acb1cb628e504dc69156' 
  AND token = 'Yy56+OHbpiFSuMNxJ2bg7mui+miYo1vUBBNicceqOMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}