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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '298313df3548ba06a3224a3a6c78bd9daa722326f8a9fff0d62255fc7d0e763d' 
  AND token = 'MMWNQx4etlzyuXAz/Go7kfGmHxwySEY+O7Wt1qVlMMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}