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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533d18d16d9ad86bb4523dc18d56ed9836e1569d37f97e1ccb08c7eacd0709cd' 
  AND token = '4EdRfrVRpVgBGinPH9r57RzDcT3coXHpuaa534Xw900=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}