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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6146ca463b552de739831b0fcbb32b97bbcc261d88da0c162a897d3c1792d6' 
  AND token = 'd/JvzVfyeTL5ZF6YF964TSdq+QQTJ2+VsSEpR8xcUEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}