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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c457f552dcd1ce8afa59e44eff673d254f505684f20e0cc9a95bdf91a5b4cf' 
  AND token = '9CdSaRg4n0gv4Ovep+OEUL/ioibxGve9YH2ZBYSQ9A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}