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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfd10b3f4729e68fe1f49d7e96258404a198cc108bf4a0f27b273924ffd02446' 
  AND token = 'Ci56xbXo2gBAIb6O02z/kEdKlY3WKMR309fGJwV+mi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}