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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '833777f5737d9d483b3bb9253b1008602cf7a1ac1f3123b2a5fe70af24caf552' 
  AND token = 'Ze+Fmt42mTG6VqKGdt6U2wxPVcC7NsPOKjCWYpyo51M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}