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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80902b8899ae5583bbcd70c00c7f925e16f7377c796c9a03949c0dbdab161b3' 
  AND token = 'eR38flz/PtdRxXBXswLot3gkZ4uYdxc28j4lYgL/99c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}